What Can Happen If You Take Too Much Valproic Acid?

How long does valproic acid stay in your system?

In healthy adults, it takes 2-3 days, on average, for most of the valproic acid to be gone from the body..

What happens if you stop taking valproic acid?

Do not stop taking valproic acid without talking to your doctor, even if you experience side effects such as unusual changes in behavior or mood or if you find out that you are pregnant. If you suddenly stop taking valproic acid, you may experience a severe, long-lasting and possibly life-threatening seizure.

Is 2000 mg of Depakote a lot?

The mean daily dose usually ranges between 1000 – 2000 mg valproate. Patients receiving daily doses higher than 45 mg/kg/day body weight should be carefully monitored.

Does Depakote help with anxiety?

Valproic Acid (Depakote) Valproic acid is an epilepsy medication that is now used for the treatment of panic attacks as well as other psychiatric problems. May work better by adding it to a primary medication that is not completely effective.

What are the adverse effects of valproic acid?

SIDE EFFECTS: See also Warning section. Diarrhea, dizziness, drowsiness, hair loss, blurred/double vision, change in menstrual periods, ringing in the ears, shakiness (tremor), unsteadiness, weight changes may occur. If any of these effects persist or worsen, tell your doctor or pharmacist promptly.

Does valproic acid help with anxiety?

It has been shown that valproic acid reduces anxiety symptoms in a 12-week open-label study in patients with social anxiety disorder [6. Valproic acid for the treatment of social anxiety disorder.

Can valproic acid cause depression?

Valproic acid may cause some people to be agitated, irritable, or display other abnormal behaviors. It may also cause some people to have suicidal thoughts and tendencies or to become more depressed. If you notice any of these side effects, tell your doctor right away.

Does valproic acid make you sleepy?

You may feel sleepy, tired or dizzy when you first start taking valproic acid. This may also happen if your dose has increased. If you’re affected, do not drive or ride a bike until you feel more alert.

What happens if Depakote levels are too high?

Unusual weight gain or loss. Tremors. Blurred or double vision, uncontrolled eye movements. Mood swings.

What happens if you overdose on Depakote?

An overdose of Depakote could be fatal, so seek immediate help or call the Poison Help Line at 1-800-222-1222 if you overdose. Overdose symptoms can include irregular heartbeat, sleepiness, and loss of consciousness resulting in a coma.

What are signs of Depakote toxicity?

CNS findings in cases of VPA overdose may include the following:Coma.Confusion.Somnolence.Worsened seizure control.Dizziness.Hallucinations.Irritability.Headache.More items…•May 30, 2020

What does Depakote do to your body?

Divalproex sodium works by increasing the amount of gamma-aminobutyric acid (GABA) in the brain. The body produces GABA naturally. It is a chemical neurotransmitter — or brain messenger. Faster than normal electrical impulses in the brain can cause erratic impulses.

Can you OD on valproic acid?

Valproate causes mild toxicity in the majority of cases. Massive overdoses of greater than 400 mg kg−1 can cause severe toxicity, but these are uncommon.

What happens if you take too much sodium valproate?

Taking too much sodium valproate can lead to symptoms such as: feeling or being sick (nausea or vomiting) headaches, or feeling dizzy. muscle weakness.

Can Depakote be stopped abruptly?

A: Do not stop taking Depakote without first talking to your doctor. Stopping Depakote suddenly can cause serious problems, including seizures that do not stop (also known as “status epilepticus”).

How much Depakote can you take in a day?

Depakote tablets are administered orally. The recommended starting dose is 250 mg twice daily. Some patients may benefit from doses up to 1,000 mg/day.

Is 1000 mg Depakote too much?

Depakote tablets are administered orally. The recommended starting dose is 250 mg twice daily. Some patients may benefit from doses up to 1,000 mg/day. In the clinical trials, there was no evidence that higher doses led to greater efficacy.

How long is Depakote in your system?

It forms a layer of gel that releases the medicine slowly. The highest level of medicine in the blood is reached in 7 to 14 hours after Depakote ER is taken.